Nov, 2023: Presentation - Hao presented lab work at the University of Washington.
Oct, 2023: Presentation - Qi, Hongjie and Fan presented lab work at Penn Epigenetics Institute Retreat.
Oct, 2023: Funding - Excited to be part of a NIH HEAL Initiative project that is supported by National Institute of Neurological Disorders and Stroke (NINDS). Link to our collaborative project: "The Penn Human Precision Pain Center (HPPC): Discovery and Functional Evaluation of Human Primary Somatosensory Neuron Types at Normal and Chronic Pain Conditions".
Sep, 2023: Presentation - Hongjie presented lab work at Leducq network grant meeting, Jackson Laboratory, Maine.
Sep, 2023: Presentation - Hao, Hongjie and Fan presented lab work at IGVF consortium annual meeting, Washington University St. Louis.
Aug, 2023: Paper - Our work "Joint single-cell profiling resolves 5mC and 5hmC and reveals their distinct gene regulatory effects" is now out at Nature Biotechnology. Emily, Peng and Qi are the co-first authors on the paper. Congratulations! Check out this tweetorial on the paper and Research Highlight at Nature Methods.
June, 2023: Presentation - Qi and Hongjie presented lab work at NHGRI AGTD meeting, San Diego.
Apr, 2023: Presentation - Hao presented lab work at the Pharmacology Seminar series, UCSF.
Apr, 2023: New member - We welcome Dr. Fan Li to join our lab as a postdoc fellow.
Feb, 2023: New member - We welcome Dr. Hongjie Zhang to join our lab as a postdoc fellow.
Dec 9, 2022: Thesis defense - Alex successfully defended his thesis (2nd PhD student gradated from the lab, NGG).
June, 2022: New member - We welcome William Gao to join our lab for doing his rotation during the summer.
Sep, 2022: Funding - Excited to be part of the ASI Ocular Surface Innervation Consortium that is supported by National Eye Institute (NEI). Link to our collaborative project: "Underpinnings of corneal innervation: anatomical, molecular, and functional studies of corneal sensory afferents in physiologic and pathologic states".
Nov 2, 2021: Presentation - Hao presented lab work on "Multi-scale Temporal Analysis of Gene Regulation in Single Cells" at the Biology of Healthy Aging Lecture, Division of Geriatric Medicine and Gerontology, Johns Hopkins University.
Oct 25, 2021: Thesis defense - Emily successfully defended her thesis (1st PhD student gradated from the lab, PGG).
Oct 7, 2021: Presentation - Hao presented lab work on "Tracking RNA regulatory dynamics and cell state transitions with metabolic labeling RNA sequencing in single cells" at 2021 Chan Zuckerberg Initiative (CZI) Single Cell Biology annual meeting.
Sep 22, 2021: New member - We welcome Mingjia Li to join our lab for doing her rotation during the Fall.
Sep 9, 2021: Funding - Happy to announce our new project funded by National Human Genome Research Institute (NHGRI) and the Impact of Genomic Variation on Function (IGVF) consortium. Our team will explore the impact of genetic variations from ancestrally diverse populations on lineage-specifying gene regulatory networks (cardiac and neural cells) using time-resolved single cell multiomics, high-throughput functional genomics and human pluripotent stem cells. If you are interested in working with us, please reach out! Press release from Penn.
Aug 27, 2021: Funding - Excited to be part of the global effort of "Pediatric Networks for the Human Cell Atlas" that is supported by Chan Zuckerberg Initiative (CZI). Link to our collaborative project: "The Childhood Hematopoiesis and Immune Development Atlas".
June, 2021: New member - We welcome Dale Brokaw and Blake Jardin to join our lab for doing their rotations during the summer.
Apr 21, 2021: Presentation - Hao presented lab work on "Mapping Neuronal Activity & RNA Dynamics with Single-cell Temporal-omics" at 10th Anniversary Alumni symposium, IDG/McGovern Institute for Brain Research at Tsinghua University.
Mar 18, 2021: Presentation - Hao presented lab work on time-resolved single-cell RNA sequencing at Penn Center for Neurodegenerative Disease Research (CNDR).
Jan 29, 2021: Presentation - Hao presented lab work on time-resolved single-cell RNA sequencing at Channing Division of Network Medicine (CDNM), Brigham and Women's Hospital & Harvard Medical School (virtual).
Jan 28, 2021: Presentation - Emily presented her work on the development of a new single-cell 5hmC sequencing method at the Neuroepigenetics Interest Group Meeting of Penn Epigenetics Institute.
Jan 27, 2021: Presentation - Hao presented our collaborative work with Dr. Jon Epstein (UPenn) at the 1st Immuno-Fib HF Network Meeting, as part of the Transatlantic Networks of Excellence Program (Leducq Foundation).
Follow this initiative here - https://twitter.com/ImmunoFibHF.
Dec 9, 2020: Presentation - Hao presented lab work at the 2020 Illumina Genomics Symposium (virtual), "Advancing Translational Research: Multifaceted Approaches to Genomics".
Oct 29, 2020: Presentation - Hao presented lab work at the 2020 EMBL Workshop (virtual), "Neuroepigenetics: From Cells to Behaviour and Disease".
Oct 12, 2020: Presentation - Hao presented lab work at the 2020 Center for Pediatric Tumor Cell Atlas (CPTCA) annual Retreat (virtual).
Learn more about our collaborative work as part of CPTCA and the Human Tumor Atlas Network (HTAN).
Sep 17, 2020: Presentation - Hao presented lab work at the 2020 CSHL meeting, "Epigenetics & Chromatin".
Aug 22, 2020: Paper - Our collaborative work with Rahul Kohli's lab at UPenn is out as part of the Methods in Molecular Biology book series (MIMB, volume 2198), "DNA Modifications: Methods and Protocols".
Jul 1, 2020: Funding - Transatlantic Networks of Excellence Program (Leducq Foundation), "The Inflammatory-Fibrosis Axis in Ischemic Heart Failure: translating mechanisms into new diagnostics and therapeutics". The project will start in Jan, 2021.
Jun 25, 2020: Presentation - Hao and Qi presented our work at two concurrent sessions of 2020 International Society for Stem Cell Research (ISSCR) meeting. Qi was also winners for both Travel Award and Merit Abstract Award of the 2020 ISSCR meeting. Penn IRM viewer guide.
Jun 11, 2020: Presentation - Peng gave a great presentation on his work at Penn Epigenetics Institute Monthly seminar.
Jun 1, 2020: Funding - Alex was awarded an F31 grant (NRSA) from NHGRI. Congratulations, Alex!
May 28, 2020: Presentation - Emily delivered a great talk at NHGRI Advanced Genomic Technology Development (AGTD) meeting.
Mar 19, 2020: Paper - Our collaborative work with Yugong Ho and Steve Liebhaber on mouse pituitary cell-type composition and lineage plasticity is now out at Protein & Cell. Peng is the co-first author on the paper. Congratulations, Peng!
Mar 2, 2020: Award - Emily won the poster award at the joint Penn Epigenetics & Immunology symposium.
Oct 23, 2019: Presentation - Jen delivered a great presentation at the genomeweb webinar series on our collaborative NCI Cancer Moonshot project with Tan Kai's group (CHOP). You can find her presentation here.
Sep 9, 2019: Presentation - Peng, Qi and Emily will present their work at our Department's Genetics Friday Research Talk series.
Aug 31, 2019: Funding - Our joint RO1 with Rahul is funded.
Aug 18, 2019: Presentation - Hao presented Alex and Emily's work at "2019 Epigenetics and Chromatin Biology" symposium in Beijing, China.
Jan 17, 2019: Presentation - Emily won the travel award and presented her work at the 2019 Keystone symposium.
Sep, 2018: Funding - Our collaborative work with Children's Hospital of Philadelphia (CHOP), "Center for pediatric tumor cell atlas (CPTCA)", is funded as part of Human Tumor Atlas Network (HTAN). Learn more about HTAN here and in this marker paper. Hao is the co-lead of the Characterization Unit of CPTCA along with Dr. Kun Zhang (UCSD).
Jun 1, 2018: Lab outing - Congratulations to Emily and Alex for passing their PhD candidacy exams!
Sep, 2017: Funding - Our lab first major NIH grant: "Charting Oxygen-Sensing Gene Regulatory Network in Cardiomyocytes Through Single-Cell Analysis and Epigenome Editing". https://commonfund.nih.gov/newinnovator/awardrecipients17